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BIF402 Assignment 1 Solution & Discussion Fall 2019  

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BIF402 Ethical and Legal Issues in Bioinformatics Assignment 1 Solution & Discussion Fall 2019


 

Course: BIF402- Ethical and Legal Issues in Bioinformatics Term: FALL 2019

Instructor: Syed Hassan Abbas Assignment #1

Assigned Date: 13-11-2019 Due Date: 25-11-2019

Total Marks: 5

 

What does the draft of HGP-Human Genome Project tell us? Also discuss the scientific and ethical implications of the HGP?

The Human Genome Project (HGP) was declared complete in April 2003. An initial rough draft of the human genome was available in June 2000 and by February 2001 a working draft had been completed and published followed by the final sequencing mapping of the human genome on April 14, 2003.

The Ethical, Legal, and Social Implications (ELSI) program was founded in 1990 as an integral part of the Human Genome Project. The mission of the ELSI program was to identify and address issues raised by genomic research that would affect individuals, families, and society. A percentage of the Human Genome Project budget at the National Institutes of Health and the U.S. Department of Energy was devoted to ELSI research.

The ELSI program focused on the possible consequences of genomic research in four main areas:

Privacy and fairness in the use of genetic information, including the potential for genetic discrimination in employment and insurance.

The integration of new genetic technologies, such as genetic testing, into the practice of clinical medicine.

Ethical issues surrounding the design and conduct of genetic research with people, including the process of inform consent.

The education of healthcare professionals, policy makers, students, and the public about genetics and the complex issues that result from genomic research.

Used to discriminate against people

Refuse to provide insurance

Ethical, legal and social implications program (1990)

 

 Question # 2: (1-Marks)

Fill following blank sections –

How does the human genome stake up?

 Organisms                           Genome Size (Bases)           Estimated Gene

Human (Homo sapiens)                        3.0                               23,000

Mouse ( M. musculus)                          2.5                               22,000

Mustard weed (A. thaliana)                  1.2                              25,500-27,000

Roundwarm (C. elegans)                      9.7                              19,100-20,000

Fruit fly ( D. melanogaster)                  1.8                              13,600-13,700

Yeast ( S. cerevisiae)                            1.2                               6,200-6,300

Bacterium (E. coli                                4.6                               4,200-4,300

 Question # 3: (2-Marks)

Read the following article (The 5 Most Pressing Ethical Issues in Biotech Medicine;

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570985/) and write summary in your own words.

ANSWER: Write summary in your own words

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