Assignment No. 3
BIO204 – Principles of Biochemical Engineering Fall 2020
Total Marks: 10
Due date: 26-01-2021
Question No. 1
Elucidate following types of fermentation: Continuous fermentation is a microbial process with a constant flow of culture medium through the reactor. The main difference compared with an animal cell perfusion process is that no device prevents the biomass from staying in the culture vessel in a continuous fermentation. The volume in a continuous fermentation is usually constant in industrial applications, but it can fluctuate in specific processes such as waste water treatment. In this type of fermentation, the continuously process is proceed and substrate and product simultansely get from the fermenter. The volume in a continuous fermentation is usually constant in industrial applications, but it can fluctuate in specific processes such as waste water treatment. The concept of continuous fermentation processes is closely linked to the chemo stat, where one nutrient is growth limiting and used to determine the growth rate. However, there are several other, less common ways by which a continuous fermentation can be controlled: through constant pH (pH-auxostat), constant optical density (turbid stat), and constant substrate.
Batch Fermentation is such a type of fermentation in which the fermentation does not carry out continuously and works in batch manner. Batch fermentation is a process where all the substrate and nutrients are added at zero time or soon after inoculation takes place, and the vessel is allowed under a controlled environment to proceed until maximum end product concentration is achieved. Batch fermentation requires frequent cleaning, sanitizing, and filling of fomenters and resulting in loss of productivity. To maintain the same productivity the initial investment for batch fermentation is higher than its continuous counterpart.
Download attachment for BIO204 assignment 3 solution file.